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PAB33688 SEPT7 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB33688
  • Application:    WB,IHC,IF,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB33688 SEPT7 Polyclonal Antibody

320.00元

Catalog : PAB33688
Application : WB,IHC,IF,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

SEPT7 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,IF,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human SEPT7

Calculated molecular weight

50kDa

Observed molecular weight 

51kDa

Swiss Prot

Q16181

Gene ID (NCBI)

989

Alternative Names

CDC10;CDC3;NBLA02942;SEPT7A


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:1000 - 1:2000

IHC

1:50 - 1:200

IF

1:50 - 1:100

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Western blot analysis of extracts of various cell lines, using SEPT7 antibody.


Immunohistochemistry of paraffin-embedded rat Intestine using SEPT7 antibody.

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Immunohistochemistry of paraffin-embedded human lung cancer using SEPT7 antibody.


Immunohistochemistry of paraffin-embedded mouse Intestine using SEPT7 antibody.

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Immunohistochemistry of paraffin-embedded mouse kidney using SEPT7 antibody.


Immunofluorescence analysis of HeLa cells using SEPT7 antibody.


Background

  

 This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.                                                                          


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.