Product name | SEPT7 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,IF,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human SEPT7 Calculated molecular weight 50kDa Observed molecular weight 51kDa Swiss Prot Q16181 Gene ID (NCBI) 989 Alternative Names CDC10;CDC3;NBLA02942;SEPT7A The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:1000 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 Western blot analysis of extracts of various cell lines, using SEPT7 antibody. Immunohistochemistry of paraffin-embedded rat Intestine using SEPT7 antibody. Immunohistochemistry of paraffin-embedded human lung cancer using SEPT7 antibody. Immunohistochemistry of paraffin-embedded mouse Intestine using SEPT7 antibody. Immunohistochemistry of paraffin-embedded mouse kidney using SEPT7 antibody. Immunofluorescence analysis of HeLa cells using SEPT7 antibody.
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
