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PAB35949 EHMT1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35949
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35949 EHMT1 Polyclonal Antibody

320.00元

Catalog : PAB35949
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

EHMT1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human EHMT1

Calculated molecular weight

7kDa/86kDa/128kDa/141kDa

Observed molecular weight 

141kDa

Swiss Prot

Q9H9B1

Gene ID (NCBI)

79813

Alternative Names

bA188C12.1;Eu-HMTase1;EUHMTASE1;FP13812;GLP;GLP1;KMT1D


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

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  Western blot analysis of extracts of various cell lines, using EHMT1 antibody.         


Background


The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.  


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.