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PAB33687 CD97 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB33687
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB33687 CD97 Polyclonal Antibody

320.00元

Catalog : PAB33687
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

CD97 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human CD97

Calculated molecular weight

81kDa/86kDa/91kDa

Observed molecular weight 

105kDa

Swiss Prot

P48960

Gene ID (NCBI)

976

Alternative Names

CD97;TM7LN1


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:200 - 1:2000

IHC

1:50 - 1:100

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Western blot analysis of extracts of various cell lines, using CD97 antibody.


Immunohistochemistry of paraffin-embedded mouse brain using CD97 antibody.


Background

  

This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.    

                                                                          

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.