Product name | RORA Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IF,ELISA,IHC |
Species reactivity | Human,Mouse |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human RORA Calculated molecular weight 53kDa/58kDa/61kDa/63kDa Observed molecular weight 63kDa Swiss Prot P35398 Gene ID (NCBI) 6095 Alternative Names NR1F1;ROR1;ROR2;ROR3;RZR-ALPHA;RZRA The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IF 1:50 - 1:200 IHC 1:50 - 1:500 Western blot analysis of extracts of various cell lines, using RORA antibody. Immunofluorescence analysis of MCF7 cells using RORA antibody. 
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
