Product name | RLN2 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,ELISA |
Species reactivity | Human,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human RLN2 Calculated molecular weight 12kDa/21kDa Observed molecular weight 21kDa Swiss Prot P04090 Gene ID (NCBI) 6019 Alternative Names bA12D24.1.1;bA12D24.1.2;H2;H2-RLX;RLXH2 The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:200 Western blot analysis of extracts of 22Rv1 cells, using RLN2 antibody. Immunohistochemistry of paraffin-embedded rat kidney using RLN2 antibody.
This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |