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PAB33682 ATP6V1B2 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB33682
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB33682 ATP6V1B2 Polyclonal Antibody

320.00元

Catalog : PAB33682
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information


Product name

ATP6V1B2 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human ATP6V1B2

Calculated molecular weight

56kDa

Observed molecular weight 

56kDa

Swiss Prot

P21281

Gene ID (NCBI)

526

Alternative Names

ATP6B1B2;ATP6B2;DOOD;HO57;VATB;Vma2;VPP3;ZLS2


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

 

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Western blot analysis of extracts of various cell lines, using ATP6V1B2 Antibody.


Background

   

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.     

                                                                        

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.