PCDHA12 Polyclonal Antibody
Lyophilized or Liquid
Immunogen Recombinant protein of human PCDHA12 Calculated molecular weight 85kDa/101kDa Observed molecular weight 102kDa Swiss Prot Q9UN75 Gene ID (NCBI) 56137 Alternative Names PCDH-ALPHA12
Recombinant protein of human PCDHA12
Calculated molecular weight
Observed molecular weight
Gene ID (NCBI)
1:500 - 1:2000
1:50 - 1:100
Western blot analysis of extracts of various cell lines, using PCDHA12 antibody.
Immunohistochemistry of paraffin-embedded human stomach using PCDHA12 antibody.
Immunohistochemistry of paraffin-embedded human trachea using PCDHA12 antibody.
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.