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PAB34931 RAD51B Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB34931
  • Application:    WB,ELISA,IHC
  • Reactivity:    Mouse,Rat

库存 800 件

PAB34931 RAD51B Polyclonal Antibody

320.00元

Catalog : PAB34931
Application : WB,ELISA,IHC
Reactivity : Mouse,Rat
Product Information


Product name

RAD51B Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human RAD51B

Calculated molecular weight

25kDa/38kDa/40kDa/42kDa

Observed molecular weight 

45kDa

Swiss Prot

O15315

Gene ID (NCBI)

5890

Alternative Names

R51H2;RAD51L1;REC2

 

Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

 

             1              

Western blot analysis of extracts of various cell lines, using RAD51B antibody.

                  

Background

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.                                                                                  

                                                                                              

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.