NODAL Polyclonal Antibody
Lyophilized or Liquid
Immunogen Recombinant protein of human NODAL Calculated molecular weight 39kDa Observed molecular weight 44kDa Swiss Prot Q96S42 Gene ID (NCBI) 4838 Alternative Names HTX5
Recombinant protein of human NODAL
Calculated molecular weight
Observed molecular weight
Gene ID (NCBI)
1:500 - 1:2000
1:50 - 1:500
Western blot analysis of extracts of various cell lines, using NODAL antibody.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.