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PAB36215 NODAL Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36215
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Rat

库存 800 件

PAB36215 NODAL Polyclonal Antibody

320.00元

Catalog : PAB36215
Application : WB,ELISA,IHC
Reactivity : Human,Rat
Product Information

 

Product name

NODAL Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human NODAL

Calculated molecular weight

39kDa

Observed molecular weight 

44kDa

Swiss Prot

Q96S42

Gene ID (NCBI)

4838

Alternative Names

HTX5


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

       blob.png

 Western blot analysis of extracts of various cell lines, using NODAL antibody.                          

 

Background


This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.  


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.