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PAB36214 HIST1H2BG Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36214
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB36214 HIST1H2BG Polyclonal Antibody

320.00元

Catalog : PAB36214
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

HIST1H2BG Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification

 

Immunogen Information


Immunogen

Recombinant protein of human HIST1H2BG

Calculated molecular weight

13kDa

Observed molecular weight 

14kDa

Swiss Prot

P62807

Gene ID (NCBI)

8339

Alternative Names

dJ221C16.8;H2B.1A;H2B/a;H2BFA


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:100 - 1:200

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Western blot analysis of extracts of various cell lines, using HIST1H2BG antibody.


Immunohistochemistry of paraffin-embedded mouse brain using HIST1H2BG antibody.

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Immunohistochemistry of paraffin-embedded human stomach using HIST1H2BG antibody.


Immunohistochemistry of paraffin-embedded rat brain using HIST1H2BG antibody.


Background


Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. 


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.