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PAB33667 PLS3 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB33667
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB33667 PLS3 Polyclonal Antibody

320.00元

Catalog : PAB33667
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

PLS3 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human PLS3

Calculated molecular weight

65kDa/69kDa/70kDa

Observed molecular weight 

71kDa

Swiss Prot

P13797

Gene ID (NCBI)

5358

Alternative Names

BMND18;T-plastin


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:200 - 1:2000

IHC

1:50 - 1:100

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Western blot analysis of extracts of various cell lines, using PLS3 antibody.


Immunohistochemistry of paraffin-embedded human stomach using PLS3 antibody.


Background

  

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.                                                                           


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.