ARHGEF11 Polyclonal Antibody
Lyophilized or Liquid
A synthetic peptide of human ARHGEF11
Calculated molecular weight
Observed molecular weight
Gene ID (NCBI)
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1:500 - 1:2000
1:50 - 1:100
Western blot analysis of extracts of mouse brain, using ARHGEF11 antibody.
Immunohistochemistry of paraffin-embedded human prostate cancer using ARHGEF11 antibody.
Immunohistochemistry of paraffin-embedded human lung using ARHGEF11 antibody.
Immunohistochemistry of paraffin-embedded human colon using ARHGEF11 antibody.
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.