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PAB35612 ARHGEF11 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35612
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35612 ARHGEF11 Polyclonal Antibody

320.00元

Catalog : PAB35612
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

ARHGEF11 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

A synthetic peptide of human ARHGEF11

Calculated molecular weight

167kDa/172kDa

Observed molecular weight 

168kDa

Swiss Prot

O15085

Gene ID (NCBI)

9826

Alternative Names

GTRAP48;PDZ-RHOGEF


Application Notes


The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

 

 1           2               

Western blot analysis of extracts of mouse brain, using ARHGEF11 antibody.


Immunohistochemistry of paraffin-embedded human prostate cancer using ARHGEF11 antibody.


3
                 4                

Immunohistochemistry of paraffin-embedded human lung using ARHGEF11 antibody.


Immunohistochemistry of paraffin-embedded human colon using ARHGEF11 antibody.

     

Background


Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.    

                                                                                               

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.