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PAB33665 GUCY2D Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB33665
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB33665 GUCY2D Polyclonal Antibody

320.00元

Catalog : PAB33665
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information


Product name

GUCY2D Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human GUCY2D

Calculated molecular weight

120kDa

Observed molecular weight 

95kDa

Swiss Prot

Q02846

Gene ID (NCBI)

3000

Alternative Names

CORD5;CORD6;CYGD;GUC1A4;GUC2D;LCA;LCA1;RCD2;retGC;RETGC-1;ROS-GC1;ROSGC


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:200 - 1:2000

IHC

1:50 - 1:500

          blob.png

Western blot analysis of extracts of various cell lines, using GUCY2D antibody. 


Background

  

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.                                                                             


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.