Product name | GUCY2D Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,ELISA,IHC |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human GUCY2D Calculated molecular weight 120kDa Observed molecular weight 95kDa Swiss Prot Q02846 Gene ID (NCBI) 3000 Alternative Names CORD5;CORD6;CYGD;GUC1A4;GUC2D;LCA;LCA1;RCD2;retGC;RETGC-1;ROS-GC1;ROSGC The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:200 - 1:2000 IHC 1:50 - 1:500 Western blot analysis of extracts of various cell lines, using GUCY2D antibody. 
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
