Product name | SOCS5 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,ELISA,IHC |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen | Recombinant protein of human SOCS5 |
Calculated molecular weight | 61kDa |
Observed molecular weight | 70kDa |
Swiss Prot | O75159 |
Gene ID (NCBI) | 9655 |
Alternative Names | CIS6;Cish5;CISH6;SOCS-5 |
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB | 1:500 - 1:2000 |
IHC | 1:50 - 1:500 |
Western blot analysis of extracts of various cell lines, using SOCS5 antibody.
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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文献链接：https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7900423/
文献题目：Exosomal miR-128-3p Promotes Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells by Targeting FOXO4 via TGF-β/SMAD and JAK/STAT3 Signaling
发表期刊：Frontiers in Cell and Developmental Biology
影响因子：5.201
DOI：10.3389/fcell.2021.568738
出版信息：Front Cell Dev Biol. 2021; 9: 568738