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PAB35610 SOCS5 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35610
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35610 SOCS5 Polyclonal Antibody

320.00元

Catalog : PAB35610
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information


Product name

SOCS5 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human SOCS5

Calculated molecular weight

61kDa

Observed molecular weight 

70kDa

Swiss Prot

O75159

Gene ID (NCBI)

9655

Alternative Names

CIS6;Cish5;CISH6;SOCS-5


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

 

           1                

Western blot analysis of extracts of various cell lines, using SOCS5 antibody.


Background


The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.                                                                                                    


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


1、

文献链接:https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7900423/

文献题目:Exosomal miR-128-3p Promotes Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells by Targeting FOXO4 via TGF/SMAD and JAK/STAT3 Signaling

发表期刊:Frontiers in Cell and Developmental Biology

影响因子:5.201

DOI10.3389/fcell.2021.568738

出版信息:Front Cell Dev Biol. 2021; 9: 568738