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PAB36208 MRPS6 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36208
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB36208 MRPS6 Polyclonal Antibody

320.00元

Catalog : PAB36208
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

MRPS6 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human MRPS6

Calculated molecular weight

14kDa

Observed molecular weight 

14kDa

Swiss Prot

P82932

Gene ID (NCBI)

64968

Alternative Names

C21orf101;MRP-S6;RPMS6;S6mt


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

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Western blot analysis of extracts of various cell lines, using MRPS6 antibody.


Immunohistochemistry of paraffin-embedded mouse heart using MRPS6 antibody.


Background


Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q.  


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.