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PAB35700 CETN3 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35700
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35700 CETN3 Polyclonal Antibody

320.00元

Catalog : PAB35700
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

CETN3 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human CETN3

Calculated molecular weight

19kDa

Observed molecular weight 

20kDa

Swiss Prot

O15182

Gene ID (NCBI)

1070

Alternative Names

CDC31;CEN3


Application Notes


   

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

 

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Western blot analysis of extracts of various cell lines, using CETN3 antibody.

 

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Immunohistochemistry of paraffin-embedded human liver injury using CETN3 antibody.


Immunohistochemistry of paraffin-embedded human lung cancer using CETN3 antibody.

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Immunohistochemistry of paraffin-embedded human stomach using CETN3 antibody.

Immunohistochemistry of paraffin-embedded rat brain using CETN3 antibody.

Immunohistochemistry of paraffin-embedded mouse kidney using CETN3 antibody.


Background

  

The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.                                                                           


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.