Product name | CETN3 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human CETN3 Calculated molecular weight 19kDa Observed molecular weight 20kDa Swiss Prot O15182 Gene ID (NCBI) 1070 Alternative Names CDC31;CEN3 The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:100 Western blot analysis of extracts of various cell lines, using CETN3 antibody. Immunohistochemistry of paraffin-embedded human liver injury using CETN3 antibody. Immunohistochemistry of paraffin-embedded human lung cancer using CETN3 antibody. Immunohistochemistry of paraffin-embedded human stomach using CETN3 antibody. Immunohistochemistry of paraffin-embedded rat brain using CETN3 antibody. Immunohistochemistry of paraffin-embedded mouse kidney using CETN3 antibody.
The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |