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PAB35699 CDH11 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35699
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35699 CDH11 Polyclonal Antibody

320.00元

Catalog : PAB35699
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

CDH11 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human CDH11

Calculated molecular weight

76kDa/87kDa

Observed molecular weight 

110kDa

Swiss Prot

P55287

Gene ID (NCBI)

1009

Alternative Names

CAD11;CDHOB;OB;OSF-4


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

 

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Western blot analysis of extracts of various cell lines, using CDH11 antibody.


Immunohistochemistry of paraffin-embedded mouse brain using CDH11 antibody.


Background

  

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.   

                                                                          

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.