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PAB34926 MAP2K5 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB34926
  • Application:    WB,IHC,IF,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB34926 MAP2K5 Polyclonal Antibody

320.00元

Catalog : PAB34926
Application : WB,IHC,IF,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

MAP2K5 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,IF,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human MAP2K5

Calculated molecular weight

46kDa/48kDa/49kDa/50kDa

Observed molecular weight 

50kDa

Swiss Prot

Q13163

Gene ID (NCBI)

5607

Alternative Names

HsT17454;MAPKK5;MEK5;PRKMK5


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

IF

1:50 - 1:100

 

  1                         

Western blot analysis of extracts of various cell lines, using MAP2K5 antibody.

 

2  3   4                  

Immunohistochemistry of paraffin-embedded rat spinal cord using MAP2K5 Antibody.

Immunohistochemistry of paraffin-embedded rat brain using MAP2K5 Antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using MAP2K5 Antibody.

    

          5                                         6

Immunohistochemistry of paraffin-embedded mouse brain using MAP2K5 Antibody.


Immunofluorescence analysis of MCF7 cells using MAP2K5 antibody.


Background

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.                             

                                                                                                 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.