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PAB35604 IRS2 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35604
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35604 IRS2 Polyclonal Antibody

320.00元

Catalog : PAB35604
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

IRS2 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human IRS2

Calculated molecular weight

137kDa

Observed molecular weight 

170kDa

Swiss Prot

Q9Y4H2

Gene ID (NCBI)

8660

Alternative Names

IRS-2


Application Notes


   

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

 

1         2                   

Western blot analysis of extracts of various cell lines, using IRS2 antibody.


Immunohistochemistry of paraffin-embedded mouse stomach using IRS2 antibody.


        3                  

Immunohistochemistry of paraffin-embedded human esophagus using IRS2 antibody.



      

Background


This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.     

                                                                                                 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.