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PAB36304-P Phospho-MAX-S11 pAb

价格:    580.00元

  • Catalog:    PAB36304-P
  • Application:    WB,IF,ELISA,IHC
  • Reactivity:    Human

库存 800 件

PAB36304-P Phospho-MAX-S11 pAb

580.00元

Catalog : PAB36304-P
Application : WB,IF,ELISA,IHC
Reactivity : Human
Product Information

 

Product name

Phospho-MAX-S11 pAb

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IF,ELISA,IHC

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

A phospho specific peptide corresponding to residues surrounding S11 of human MAX

Calculated molecular weight

9kDa/11kDa/12kDa/15kDa/17kDa/18kDa

Observed molecular weight 

18kDa

Swiss Prot

P61244

Gene ID (NCBI)

4149

Alternative Names

bHLHd4


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IF

1:50 - 1:200

IHC

1:50 - 1:500

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Western blot analysis of extracts of Jurkat cells, using Phospho-MAX-S11 antibody.


Immunofluorescence analysis of U2OS cells using Phospho-MAX-S11 antibody.


Background


The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.   


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.