Product name | Phospho-MAX-S11 pAb |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IF,ELISA,IHC |
Species reactivity | Human |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen | A phospho specific peptide corresponding to residues surrounding S11 of human MAX |
Calculated molecular weight | 9kDa/11kDa/12kDa/15kDa/17kDa/18kDa |
Observed molecular weight | 18kDa |
Swiss Prot | P61244 |
Gene ID (NCBI) | 4149 |
Alternative Names | bHLHd4 |
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB | 1:500 - 1:2000 |
IF | 1:50 - 1:200 |
IHC | 1:50 - 1:500 |
Western blot analysis of extracts of Jurkat cells, using Phospho-MAX-S11 antibody. | Immunofluorescence analysis of U2OS cells using Phospho-MAX-S11 antibody. |
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
