Product name | WHSC1 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,ELISA |
Species reactivity | Human,Mouse |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human WHSC1 Calculated molecular weight 30kDa/53kDa/66kDa/69kDa/71kDa/80kDa/152kDa Observed molecular weight 80kDa, 152kDa Swiss Prot O96028 Gene ID (NCBI) 7468 Alternative Names KMT3F;KMT3G;MMSET;REIIBP;TRX5;WHS;WHSC1;MMSET;NSD2;REIIBP;TRX5;WHS The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:200 Western blot analysis of extracts of various cell lines, using WHSC1 antibody. Immunohistochemistry of paraffin-embedded mouse lung using WHSC1 antibody. Immunohistochemistry of paraffin-embedded mouse kidney using WHSC1 antibody.
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |