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PAB35598 WHSC1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35598
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse

库存 800 件

PAB35598 WHSC1 Polyclonal Antibody

320.00元

Catalog : PAB35598
Application : WB,IHC,ELISA
Reactivity : Human,Mouse
Product Information


Product name

WHSC1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human WHSC1

Calculated molecular weight

30kDa/53kDa/66kDa/69kDa/71kDa/80kDa/152kDa

Observed molecular weight 

80kDa, 152kDa

Swiss Prot

O96028

Gene ID (NCBI)

7468

Alternative Names

KMT3F;KMT3G;MMSET;REIIBP;TRX5;WHS;WHSC1;MMSET;NSD2;REIIBP;TRX5;WHS


Application Notes


The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

 

     1                      

Western blot analysis of extracts of various cell lines, using WHSC1 antibody.  

   2                       3

Immunohistochemistry of paraffin-embedded mouse lung using WHSC1 antibody.


Immunohistochemistry of paraffin-embedded mouse kidney using WHSC1 antibody.

     

Background


This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.   

                                                                                                 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.