Lyophilized or Liquid
A phospho specific peptide corresponding to residues surrounding S412 of human MAP3K7
Calculated molecular weight
Observed molecular weight
Gene ID (NCBI)
1:500 - 1:2000
1:50 - 1:500
Western blot analysis of extracts of K-562 cells, using Phospho-MAP3K7-S412 antibody.
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.