CAPN10 Polyclonal Antibody
Lyophilized or Liquid
Immunogen Recombinant protein of human CAPN10 Calculated molecular weight 15kDa/29kDa/49kDa/57kDa/60kDa/74kDa Observed molecular weight 75kDa Swiss Prot Q9HC96 Gene ID (NCBI) 11132 Alternative Names CANP10;NIDDM1
Recombinant protein of human CAPN10
Calculated molecular weight
Observed molecular weight
Gene ID (NCBI)
1:1000 - 1:4000
1:50 - 1:500
Western blot analysis of extracts of various cell lines, using CAPN10 antibody.
Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.