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PAB35686 CAV3 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35686
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35686 CAV3 Polyclonal Antibody

320.00元

Catalog : PAB35686
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

CAV3 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human CAV3

Calculated molecular weight

17kDa

Observed molecular weight 

17kDa

Swiss Prot

P56539

Gene ID (NCBI)

859

Alternative Names

LGMD1C;LQT9;VIP-21;VIP21


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

 

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Western blot analysis of extracts of various cell lines, using CAV3 antibody.


Immunohistochemistry of paraffin-embedded human colon using CAV3 antibody.

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Immunohistochemistry of paraffin-embedded mouse lung using CAV3 antibody.




Background

  

This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.                                                                           

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.