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PAB36193 KCNE2 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36193
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse

库存 800 件

PAB36193 KCNE2 Polyclonal Antibody

320.00元

Catalog : PAB36193
Application : WB,ELISA,IHC
Reactivity : Human,Mouse
Product Information

 

Product name

KCNE2 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

A synthetic peptide of human KCNE2

Calculated molecular weight

14kDa

Observed molecular weight 

15kDa

Swiss Prot

Q9Y6J6

Gene ID (NCBI)

9992

Alternative Names

ATFB4;LQT5;LQT6;MIRP1


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

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Western blot analysis of extracts of U-251MG cells, using KCNE2 antibody.                           

 


Background


Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia.  


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.