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PAB36299-P Phospho-MAP2K1-S298 pAb

价格:    580.00元

  • Catalog:    PAB36299-P
  • Application:    WB,IP,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB36299-P Phospho-MAP2K1-S298 pAb

580.00元

Catalog : PAB36299-P
Application : WB,IP,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

Phospho-MAP2K1-S298 pAb

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IP,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

A phospho specific peptide corresponding to residues surrounding S298 of human MAP2K1

Calculated molecular weight

40kDa/43kDa

Observed molecular weight 

43kDa

Swiss Prot

Q02750

Gene ID (NCBI)

5604

Alternative Names

CFC3;MAPKK1;MEK1;MKK1;PRKMK1


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IP

1:50 - 1:100

IHC

1:50 - 1:500


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Western blot analysis of extracts of various cell lines, using Phospho-MAP2K1-S298 antibody.

Western blot analysis of extracts of various cell lines, using Phospho-MAP2K1-S298 antibody.

Immunoprecipitation analysis of 200ug extracts of 293 cells treated by PMA using 2.5ug Phospho-MAP2K1-S298 antibody.


Background


The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.   


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.