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PAB35685 CKMT2 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35685
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35685 CKMT2 Polyclonal Antibody

320.00元

Catalog : PAB35685
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

CKMT2 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human CKMT2

Calculated molecular weight

47kDa

Observed molecular weight 

48kDa

Swiss Prot

P17540

Gene ID (NCBI)

1160

Alternative Names

SMTCK


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:20 - 1:200

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Western blot analysis of extracts of various cell lines, using CKMT2 antibody.


Immunohistochemistry of paraffin-embedded rat heart using CKMT2 antibody.

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Immunohistochemistry of paraffin-embedded human esophagus using CKMT2 antibody.


Immunohistochemistry of paraffin-embedded mouse heart using CKMT2 antibody.


Background

  

   Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.                                                                      


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.