Product name | AURKC Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen A synthetic peptide of human AURKC Calculated molecular weight 32kDa/33kDa/35kDa Observed molecular weight 36kDa Swiss Prot Q9UQB9 Gene ID (NCBI) 6795 Alternative Names AIE2;AIK3;ARK3;AurC;aurora-C;HEL-S-90;SPGF5;STK13 The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:100 Western blot analysis of extracts of various cell lines, using AURKC antibody. Immunohistochemistry of paraffin-embedded rat kidney using AURKC antibody. Immunohistochemistry of paraffin-embedded rat brain using AURKC antibody.
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |