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PAB35594 SSX4 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35594
  • Application:    WB,ELISA,IHC
  • Reactivity:    Mouse

库存 800 件

PAB35594 SSX4 Polyclonal Antibody

320.00元

Catalog : PAB35594
Application : WB,ELISA,IHC
Reactivity : Mouse
Product Information


Product name

SSX4 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Mouse

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human SSX4

Calculated molecular weight

17kDa/21kDa

Observed molecular weight 

27kDa

Swiss Prot

O60224

Gene ID (NCBI)

6759

Alternative Names

CT5.4


Application Notes


The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

 

              1             

Western blot analysis of extracts of various cell lines, using SSX4 antibody.

     

Background


The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.   

                                                                                                 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.