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PAB35591 SORT1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35591
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35591 SORT1 Polyclonal Antibody

320.00元

Catalog : PAB35591
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

SORT1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human SORT1

Calculated molecular weight

77kDa/92kDa

Observed molecular weight 

100kDa

Swiss Prot

Q99523

Gene ID (NCBI)

6272

Alternative Names

Gp95;LDLCQ6;NT3;NTR3


Application Notes


The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

 

1           2                        

Western blot analysis of extracts of various cell lines, using SORT1 antibody.


Immunohistochemistry of paraffin-embedded human kidney using SORT1 antibody.

 

   3                

Immunohistochemistry of paraffin-embedded mouse liver using SORT1 antibody.



     

Background


This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants.       

                                                                                                 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.