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PAB34918 PDHB Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB34918
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB34918 PDHB Polyclonal Antibody

320.00元

Catalog : PAB34918
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information


Product name

PDHB Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human PDHB

Calculated molecular weight

37kDa/39kDa

Observed molecular weight 

39kDa

Swiss Prot

P11177

Gene ID (NCBI)

5162

Alternative Names

PDHBD;PDHE1-B;PHE1B


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

 

     1                      

Western blot analysis of extracts of various cell lines, using PDHB antibody.

                

Background


              The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene.                                                                                     


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.