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PAB35588 PRSS2 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35588
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse

库存 800 件

PAB35588 PRSS2 Polyclonal Antibody

320.00元

Catalog : PAB35588
Application : WB,ELISA,IHC
Reactivity : Human,Mouse
Product Information


Product name

PRSS2 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human PRSS2

Calculated molecular weight

26kDa

Observed molecular weight 

26kDa

Swiss Prot

P07478

Gene ID (NCBI)

5645

Alternative Names

TRY2;TRY8;TRYP2


Application Notes


 

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

 

          1                 

Western blot analysis of extracts of various cell lines, using PRSS2 antibody.

    

Background


This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.                                                                                                       


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.