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PAB34914 HNRNPM Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB34914
  • Application:    WB,IHC,IF,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB34914 HNRNPM Polyclonal Antibody

320.00元

Catalog : PAB34914
Application : WB,IHC,IF,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

HNRNPM Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,IF,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human HNRNPM

Calculated molecular weight

73kDa/77kDa

Observed molecular weight 

78kDa

Swiss Prot

P52272

Gene ID (NCBI)

4670

Alternative Names

CEAR;hnRNPM;HNRNPM4;HNRPM;HNRPM4;HTGR1;NAGR1

 

Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

IF

1:50 - 1:200

 

1 2 3                       

Western blot analysis of extracts of various cell lines, using HNRNPM antibody.

Immunohistochemistry of paraffin-embedded rat brain using HNRNPM antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using HNRNPM antibody.

 

4   5  6              

Immunohistochemistry of paraffin-embedded human colon carcinoma using HNRNPM antibody.

Immunohistochemistry of paraffin-embedded human esophageal cancer using HNRNPM antibody.

Immunohistochemistry of paraffin-embedded mouse kidney using HNRNPM antibody.

7                 8

Immunohistochemistry of paraffin-embedded mouse heart using HNRNPM antibody.


Immunofluorescence analysis of MCF7 cells using HNRNPM antibody.


Background


          This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants                                                                                       


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.