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PAB36177 MYO5A Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36177
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB36177 MYO5A Polyclonal Antibody

320.00元

Catalog : PAB36177
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

MYO5A Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human MYO5A

Calculated molecular weight

212kDa/215kDa/218kDa

Observed molecular weight 

215kDa

Swiss Prot

Q9Y4I1

Gene ID (NCBI)

4644

Alternative Names

GS1;MYH12;MYO5;MYR12


Application Notes


The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

 

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Western blot analysis of extracts of various cell lines, using MYO5A antibody.


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Immunohistochemistry of paraffin-embedded rat kidney using MYO5A antibody.


Immunohistochemistry of paraffin-embedded human liver cancer using MYO5A antibody.

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Immunohistochemistry of paraffin-embedded human prostate cancer using MYO5A antibody.


Immunohistochemistry of paraffin-embedded human rectum using MYO5A antibody.

 


 

Background


This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined. 


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.