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PAB35681 CPS1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35681
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35681 CPS1 Polyclonal Antibody

320.00元

Catalog : PAB35681
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

CPS1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human CPS1

Calculated molecular weight

116kDa/164kDa/165kDa

Observed molecular weight 

165kDa

Swiss Prot

P31327

Gene ID (NCBI)

1373

Alternative Names

CPSASE1;PHN


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:1000 - 1:2000

IHC

1:50 - 1:200

 

        blob.png                   

Western blot analysis of extracts of various cell lines, using CPS1 antibody.


Background

  

   The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.                                                                             


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.