Product name | CPS1 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human CPS1 Calculated molecular weight 116kDa/164kDa/165kDa Observed molecular weight 165kDa Swiss Prot P31327 Gene ID (NCBI) 1373 Alternative Names CPSASE1;PHN The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:1000 - 1:2000 IHC 1:50 - 1:200 Western blot analysis of extracts of various cell lines, using CPS1 antibody.
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |