Lyophilized or Liquid
A phospho specific peptide corresponding to residues surrounding Y1284 of human HER4
Calculated molecular weight
Observed molecular weight
Gene ID (NCBI)
1:500 - 1:2000
1:50 - 1:500
Western blot analysis of extracts of A-431 cells, using Phospho-ERBB4-Y1284 antibody.
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.