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PAB35675 LEPREL1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35675
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35675 LEPREL1 Polyclonal Antibody

320.00元

Catalog : PAB35675
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information


Product name

LEPREL1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human LEPREL1

Calculated molecular weight

60kDa/80kDa

Observed molecular weight 

85kDa

Swiss Prot

Q8IVL5

Gene ID (NCBI)

55214

Alternative Names

LEPREL1;MCVD;MLAT4


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

 

                blob.png           

Western blot analysis of extracts of NCI-H460 cells, using LEPREL1 antibody.


Background

  

This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.                                                                            


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.