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PAB36164 DSG1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36164
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human

库存 800 件

PAB36164 DSG1 Polyclonal Antibody

320.00元

Catalog : PAB36164
Application : WB,IHC,ELISA
Reactivity : Human
Product Information

 

Product name

DSG1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human DSG1

Calculated molecular weight

42kDa/113kDa

Observed molecular weight 

150kDa

Swiss Prot

Q02413

Gene ID (NCBI)

1828

Alternative Names

CDHF4;DG1;DSG;EPKHE;EPKHIA;PPKS1;SPPK1


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

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Western blot analysis of extracts of various cell lines, using DSG1 antibody.


Immunohistochemistry of paraffin-embedded human trachea using DSG1 antibody.


Background


This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.  


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.