Product name | LGALS3BP Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IF,ELISA,IHC |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human LGALS3BP Calculated molecular weight 65kDa Observed molecular weight 75kDa, 110kDa Swiss Prot Q08380 Gene ID (NCBI) 3959 Alternative Names 90K;BTBD17B;CyCAP;gp90;M2BP;MAC-2-BP;TANGO10B The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IF 1:50 - 1:100 IHC 1:50 - 1:500 Western blot analysis of extracts of various cell lines, using LGALS3BP antibody. Immunofluorescence analysis of MCF7 cells using LGALS3BP antibody.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
