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PAB34905 KCND3 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB34905
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB34905 KCND3 Polyclonal Antibody

320.00元

Catalog : PAB34905
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

KCND3 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human KCND3

Calculated molecular weight

71kDa/73kDa

Observed molecular weight 

73kDa

Swiss Prot

Q9UK17

Gene ID (NCBI)

3752

Alternative Names

BRGDA9;KCND3L;KCND3S;KSHIVB;KV4.3;SCA19;SCA22

 

Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

 

 1                2                 

Western blot analysis of extracts of various cell lines, using KCND3 antibody.


Immunohistochemistry of paraffin-embedded mouse brain using KCND3 antibody.

                    

Background


Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.                                                                                                            

                                                                                                  

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.