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PAB36279-P Phospho-EGFR-Y845 pAb

价格:    580.00元

  • Catalog:    PAB36279-P
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human

库存 800 件

PAB36279-P Phospho-EGFR-Y845 pAb

580.00元

Catalog : PAB36279-P
Application : WB,ELISA,IHC
Reactivity : Human
Product Information

 

Product name

Phospho-EGFR-Y845 pAb

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

A phospho specific peptide corresponding to residues surrounding Y845 of human EGFR

Calculated molecular weight

44kDa/69kDa/77kDa/134kDa

Observed molecular weight 

200kDa

Swiss Prot

P00533

Gene ID (NCBI)

1956

Alternative Names

ERBB;ERBB1;HER1;mENA;NISBD2;PIG61


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

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Western blot analysis of extracts of A-431 cells, using Phospho-EGFR-Y845 antibody.




Background


 

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.  



Storage



Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.