Product name | ITPR1 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,ELISA,IHC |
Species reactivity | Human,Mouse |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen A synthetic peptide of human ITPR1 Calculated molecular weight 306-313kDa Observed molecular weight 315kDa Swiss Prot Q14643 Gene ID (NCBI) 3708 Alternative Names ACV;CLA4;INSP3R1;IP3R;IP3R1;PPP1R94;SCA15;SCA16;SCA29 The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:500 Western blot analysis of extracts of various cell lines, using ITPR1 antibody.
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |