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PAB36136 PHLPP1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36136
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB36136 PHLPP1 Polyclonal Antibody

320.00元

Catalog : PAB36136
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

PHLPP1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human PHLPP1

Calculated molecular weight

133kDa/184kDa

Observed molecular weight 

185kDa

Swiss Prot

O60346

Gene ID (NCBI)

23239

Alternative Names

PHLPP;PLEKHE1;PPM3A;SCOP


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500



    blob.png

Western blot analysis of extracts of various cell lines, using PHLPP1 antibody.


Background


This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. 

 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.