Product name | EYA3 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human EYA3 Calculated molecular weight 48kDa/56kDa/57kDa/58kDa/62kDa Observed molecular weight 63kDa Swiss Prot Q99504 Gene ID (NCBI) 2140 Alternative Names EYA3, Eyes absent homolog 3 The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:200 Western blot analysis of extracts of various cell lines, using EYA3 antibody. Immunohistochemistry of paraffin-embedded rat kidney using EYA3 antibody. Immunohistochemistry of paraffin-embedded human kidney using EYA3 antibody. Immunohistochemistry of paraffin-embedded human gastric using EYA3 antibody. Immunohistochemistry of paraffin-embedded mouse liver using EYA3 antibody. 
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
