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PAB35566 EYA3 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35566
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35566 EYA3 Polyclonal Antibody

320.00元

Catalog : PAB35566
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

EYA3 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human EYA3

Calculated molecular weight

48kDa/56kDa/57kDa/58kDa/62kDa

Observed molecular weight 

63kDa

Swiss Prot

Q99504

Gene ID (NCBI)

2140

Alternative Names

EYA3, Eyes absent homolog 3


Application Notes


The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

 

1          2                   

Western blot analysis of extracts of various cell lines, using EYA3 antibody.


Immunohistochemistry of paraffin-embedded rat kidney using EYA3 antibody.


3
  4   5              

Immunohistochemistry of paraffin-embedded human kidney using EYA3 antibody.

Immunohistochemistry of paraffin-embedded human gastric using EYA3 antibody.

Immunohistochemistry of paraffin-embedded mouse liver using EYA3 antibody.

     

Background


This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.                                                                                                         


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.