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PAB36132 CSE1L Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36132
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human

库存 800 件

PAB36132 CSE1L Polyclonal Antibody

320.00元

Catalog : PAB36132
Application : WB,ELISA,IHC
Reactivity : Human
Product Information

 

Product name

CSE1L Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

A synthetic peptide of human CSE1L

Calculated molecular weight

22kDa/103kDa/107kDa/110kDa

Observed molecular weight 

110kDa

Swiss Prot

P55060

Gene ID (NCBI)

1434

Alternative Names

CAS;CSE1;XPO2


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500



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Western blot analysis of extracts of various cell lines, using CSE1L antibody.

 

Background


Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.  

 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.