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PAB35563 DNM2 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35563
  • Application:    WB,ELISA,IHC
  • Reactivity:    Mouse,Rat

库存 800 件

PAB35563 DNM2 Polyclonal Antibody

320.00元

Catalog : PAB35563
Application : WB,ELISA,IHC
Reactivity : Mouse,Rat
Product Information


Product name

DNM2 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human DNM2

Calculated molecular weight

97kDa/98kDa

Observed molecular weight 

98kDa

Swiss Prot

P50570

Gene ID (NCBI)

1785

Alternative Names

CMT2M;CMTDI1;CMTDIB;DI-CMTB;DYN2;DYNII;LCCS5


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

 

              1             

Western blot analysis of extracts of various cell lines, using DNM2 Antibody.

     

Background


Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.                                                                                                   


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.