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PAB35558 CDH16 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35558
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35558 CDH16 Polyclonal Antibody

320.00元

Catalog : PAB35558
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

CDH16 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human CDH16

Calculated molecular weight

79kDa/85kDa/87kDa/89kDa

Observed molecular weight 

110kDa

Swiss Prot

O75309

Gene ID (NCBI)

1014

Alternative Names

cadherin 16, KSP cadherin, Cadherin-16, CDH16, Kidney specific cadherin, Ksp cadherin


Application Notes


 

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

 

  1                         

Western blot analysis of extracts of various cell lines, using CDH16 antibody.

2                           3

Immunohistochemistry of paraffin-embedded rat brain using CDH16 antibody.


Immunohistochemistry of paraffin-embedded rat kidney using CDH16 antibody.

4    5    6

Immunohistochemistry of paraffin-embedded rat heart using CDH16 antibody.

Immunohistochemistry of paraffin-embedded mouse brain using CDH16 antibody.

Immunohistochemistry of paraffin-embedded mouse kidney using CDH16 antibody.

    

Background


This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.         

                                                                                                 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.