Product name | CDH16 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human CDH16 Calculated molecular weight 79kDa/85kDa/87kDa/89kDa Observed molecular weight 110kDa Swiss Prot O75309 Gene ID (NCBI) 1014 Alternative Names cadherin 16, KSP cadherin, Cadherin-16, CDH16, Kidney specific cadherin, Ksp cadherin The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:200 Western blot analysis of extracts of various cell lines, using CDH16 antibody. Immunohistochemistry of paraffin-embedded rat brain using CDH16 antibody. Immunohistochemistry of paraffin-embedded rat kidney using CDH16 antibody. Immunohistochemistry of paraffin-embedded rat heart using CDH16 antibody. Immunohistochemistry of paraffin-embedded mouse brain using CDH16 antibody. Immunohistochemistry of paraffin-embedded mouse kidney using CDH16 antibody.
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |