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PAB36130 IMPDH1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36130
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB36130 IMPDH1 Polyclonal Antibody

320.00元

Catalog : PAB36130
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

IMPDH1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human IMPDH1

Calculated molecular weight

52kDa/54kDa/55kDa/60kDa/63kDa/64kDa

Observed molecular weight 

55kDa

Swiss Prot

P20839

Gene ID (NCBI)

3614

Alternative Names

IMPD;IMPD1;IMPDH-I;LCA11;RP10;sWSS2608;IMPD;IMPD1;LCA11;RP10;sWSS2608


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:1000 - 1:2000

IHC

1:50 - 1:500



     blob.png

Western blot analysis of extracts of various cell lines, using IMPDH1 antibody.


Background


The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.