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PAB35556 BPGM Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35556
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35556 BPGM Polyclonal Antibody

320.00元

Catalog : PAB35556
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

BPGM Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human BPGM

Calculated molecular weight

30kDa

Observed molecular weight 

30kDa

Swiss Prot

P07738

Gene ID (NCBI)

669

Alternative Names

DPGM


Application Notes


The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

 

    1                       

Western blot analysis of extracts of various cell lines, using BPGM antibody.


               2

Immunohistochemistry of paraffin-embedded human stomach using BPGM antibody.



     

Background


 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.                                                                                                  


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.