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PAB35553 ANGPT1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35553
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse

库存 800 件

PAB35553 ANGPT1 Polyclonal Antibody

320.00元

Catalog : PAB35553
Application : WB,IHC,ELISA
Reactivity : Human,Mouse
Product Information


Product name

ANGPT1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human ANGPT1

Calculated molecular weight

57kDa

Observed molecular weight 

51kDa

Swiss Prot

Q15389

Gene ID (NCBI)

284

Alternative Names

AGP1, AGPT, ANG 1, ANG1, angiopoietin 1, ANGPT1, KIAA0003


Application Notes


 

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

 

          1                         2 

Western blot analysis of extracts of various cell lines, using ANGPT1 antibody.


Immunohistochemistry of paraffin-embedded rat lung using ANGPT1 antibody.


  3             4                

Immunohistochemistry of paraffin-embedded human esophagus using ANGPT1 antibody.


Immunohistochemistry of paraffin-embedded mouse lung using ANGPT1 antibody.

    

Background


 This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.                                                                                                


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.