Product name | ANGPT1 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,ELISA |
Species reactivity | Human,Mouse |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human ANGPT1 Calculated molecular weight 57kDa Observed molecular weight 51kDa Swiss Prot Q15389 Gene ID (NCBI) 284 Alternative Names AGP1, AGPT, ANG 1, ANG1, angiopoietin 1, ANGPT1, KIAA0003 The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:100 Western blot analysis of extracts of various cell lines, using ANGPT1 antibody. Immunohistochemistry of paraffin-embedded rat lung using ANGPT1 antibody. Immunohistochemistry of paraffin-embedded human esophagus using ANGPT1 antibody. Immunohistochemistry of paraffin-embedded mouse lung using ANGPT1 antibody.
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |